Year: 2024
Type: article
Study design: Observational Study
Abstract: Background:The relation between LDL-cholesterol levels and mortality in patients presenting with intracerebral hemorrhage (ICH) has not been made explicitly clear.This study is aimed at inquiring about the lipid profiles of patients with hemorrhagic stroke in relation to 30-day mortality.Methods: This is a 2-year cross-sectional observational study among 100 patients with acute ICH who were admitted into the Department of Medicine at S.C.B. Medical College and Hospital from August 2019 to October 2021.The patient profile will be evaluated in terms of demographic data, clinical presentations, lipid profiles, and characteristics of ICH.Statistical analyses will be carried out to compare lipid levels between survivors and nonsurvivors.Results: The cohort was 70% male, 30% female, aged 62.02 ± 10.34 years.Motor symptoms were usually reported in presentations; the mortality rate was significant at 51%.While there is some evidence of mean total cholesterol, triglycerides, and LDL levels, none of them was found to be statistically significant related to mortality except for HDL and VLDL, which are significant at p = 0.011 and p = 0.000, respectively.ICH volume showed a significant correlation with mortality. Conclusions:The results indicate that whereas lipid profiles, particularly HDL and VLDL, may play a role in determining outcomes of ICH, hemorrhage volume is the most significant determinant of mortality.More such researches are indeed warranted to understand the underlying mechanisms as well as clinical implications of these associations.
Author: Dr Pranay Kumar Patro
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405209169