Predictors of Retention in the 1Florida Alzheimer’s Disease Research Center (ADRC) Over Two Waves
Year: 2024
Type: article
Study design: Observational Study
Abstract: Background: Attrition is a significant methodological concern in longitudinal studies. Sample loss can limit generalizability and compromise internal validity. Methods: Wave one ( n = 346) and wave two follow-ups ( n = 196) of the 1Florida ADRC clinical core were examined using a 24-month visit window. Results: The sample (59% Hispanic) demonstrated retention rates of 77.2% and 86.2% in waves one and two, respectively. Predictors of lower retention in wave one included older age, amnestic MCI or dementia, and lower cognition and function scores. Completing a baseline MRI and lack of hippocampal atrophy were associated with higher retention in both waves. In wave two, a greater neighborhood disadvantage score was associated with attrition. Discussion: Predictors of retention changed over time, possibly due to the early withdrawal of the most vulnerable in the initial wave. Understanding predictors of retention can facilitate retention strategies, reduce attrition, and increase the validity of findings.
Source: Journal of Applied Gerontology
Authors: Shanna L. Burke, Warren Barker, Adrienne Grudzien, Maria T. Greig-Custo, Raquel Behar, Rosemarie A. Rodriguez, Monica Rosselli, Idaly Velez Uribe, David A. Loewenstein, Miriam J. Rodriguez, Cesar Chirinos, Carlos Quinonez, Joanna Gonzalez, Yaimara Gonzalez Pineiro, Mileidys Herrera, Malek Adjouadi, Michael Marsiske, Ranjan Duara
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G1048051091, G1917323781, G330755320, MRI: Development of an Instrument for a Comprehensive Study of Alzheimer's Disease: Multimodal Imaging, Visualization, Machine Learning and Therapeutic Brain Stimulation, University of Florida - Mt. Sinai Medical Center AD Research Center, G9000079798, G9000274623, G999084852
OpenAlex ID: W4405222048