Synthesis, Identification some of new heterocyclic Compounds Derivatives and study of the biological Activity
Year: 2024
Type: article
Abstract: This research includes prepeared of some new heterocyclic compounds from 2-hydroxy napthaldehyde with 2-amino thiazol , 2-amino thiazol reacted with 2-hydroxy napthaldehyde , to produce shiff base derivative (R),(R) using to synthesis of some new heterocyclic derivatives by reactions and reactant with types solvent and materials to synthesis heterocyclic membered ring , first step : Involved synthesis of seven heterocyclic compounds by reacting (R) with phthalic ,succinic and malic anhydride respectfully to prepeared oxazepine compounds (R1,R2,R3) . Second step involves preparing of five- heterocyclic derivatives by reacting (R) with amino acid glycine and thyrocine in tetra hydro furan to prepare (R4,R5).Third step includes preparing of four heterocyclic compounds β-lactam(S6). All the compounds were characterized by FT-IR ,H1NMR,13CNMR .Also compounds were studied the measurement antibacterial activity.
Authors: Rusul Ali Muhammad, Rajaa A. A. Ghafil
Institution: University of Kufa
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4405239015