Work

Synthesis, Antibacterial Evaluation and Study Molecular Docking of New derivatives from sulfapyridine

Year: 2024

Type: article

Abstract: Sulfa pyridine is a sulfa-derived antibiotic. It works to inhibit the activity and reproduction of bacterial cells, by inhibiting the production of some enzymes that bacteria need for their growth and activity. Therefore, in this research, we decided to increase the effectiveness of the Sulfa pyridine compound by adding some groups such as azomethine, as well as preparing some derivatives of thiazolidinone and derivatives , thiazine, hydroquinazolone, and oxazepine, Then evaluating the effectiveness of some prepared derivatives against two types of gram-negative and gram-positive bacteria, such as E. coli and Staphylococcus aureus and molecular docking study against skin cancer .

Source: Journal of Kufa for Chemical Sciences

DOI: 10.36329/jkcm/2024/v3.i3.15832

Authors: Maryam Methaq Najm, Hanan Faleh Mohsein

Institution: University of Kufa

Language: English

Topic: Synthesis and Biological Evaluation

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: University of Kufa