Work

A Case of Transthyretin Cardiac Amyloidosis Coexisting With Rheumatoid Arthritis

Year: 2024

Type: article

Abstract: Cardiac amyloidosis is a rare but increasingly recognized cause of heart failure, often underdiagnosed until later stages of the disease. This report describes a case of transthyretin amyloidosis (ATTR) in a 68-year-old male patient with a significant medical history of rheumatoid arthritis (RA), a combination seldom documented in the literature. The patient presented with progressive symptoms of heart failure, and diagnostic testing confirmed ATTR cardiac amyloidosis through pyrophosphate (PYP) scanning. This case highlights the clinical presentation, diagnostic process, and management of cardiac amyloidosis while exploring a potential link between RA and amyloid deposition. Early recognition of cardiac amyloidosis is crucial for improving outcomes, especially in patients with coexisting systemic inflammatory conditions like RA.

Source: Cureus

DOI: 10.7759/cureus.75443

Authors: Yongdeok B Shin, Jenna McAllister

Institution: Mary Washington Hospital

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405247190