FDG PET/CT and MRI of IgG4-Related Disease Presenting as a Hepatic Solitary Solid Mass
Year: 2024
Type: article
Study design: Case Report
Abstract: A hepatic solitary solid mass mimicking malignancy was discovered through MRI and FDG PET/CT in a 76-year-old woman with abdominal pain and no abnormal tumor markers in the blood. She underwent surgery to remove the lesion. Histopathology with biopsy was highly suspicious for IgG4-related disease, although immunohistochemical staining demonstrated non–IgG4-positive plasma cells. Finally, intrahepatic IgG4-related disease was supported by elevated serum IgG4 of 141 mg/dL. IgG4-related disease could manifest as hepatic solitary solid mass without any other organ involvement, and the immunohistochemical staining of IgG4 may be negative.
Source: Clinical nuclear medicine open.
Authors: Wanjun Ma, Yongjun Luo, Furong Wang, Jiangyan Liu
Institution: Lanzhou University Second Hospital
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4405274242