Work

Polymers Facilitating Therapeutic Efficacy and Applications for Traditional Chinese Medicine

Year: 2024

Type: article

Abstract: ABSTRACT The active ingredients from traditional Chinese medicine (TCM) are fundamental to its therapeutic efficacy. However, their difficult detection, low solubility, poor stability, uncertain biocompatibility, and inefficient absorption rate, hinder their clinical application. Polymers have emerged as a viable solution to these issues, providing a platform for the detection, enrichment, and exertion of pharmacological effects. This review delves into the application of polymers in active ingredients from TCM, covering various aspects including molecularly imprinted polymers (MIPs), polymer micelles, polymer hydrogels, conjugated polymers, and polymer nanoparticles (NPs). These advanced systems leverage the designability, adjustable solubility, and biocompatibility of polymers to enhance the therapeutic potential of TCM. The review concludes by discussing the current challenges and prospects of using polymers in TCM. It aims to provide a comprehensive understanding of the field, highlighting the potential of polymers to revolutionize TCM practices and contribute to the modernization of TCM.

Source: Journal of Polymer Science

DOI: 10.1002/pol.20240904

Authors: Cong Li, Zhi Luo, Hongqing Feng, Zhou Li

Institutions: Chinese Academy of Sciences, Beijing Institute of Nanoenergy and Nanosystems, China Academy of Chinese Medical Sciences, Institute of Chinese Materia Medica, Southern University of Science and Technology

Language: English

Topic: Advanced Drug Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,170