Work

Transcriptional signature of a hypersensitive glucocorticoid receptor variant in the neuroendocrine system suggests enhanced vulnerability to brain disorders

Year: 2024

Type: article

Abstract: provides strong evidence that GR hypersensitivity leads to increased susceptibility to brain disorders.

Source: Brain Behavior and Immunity

DOI: 10.1016/j.bbi.2024.12.004

Authors: Eduard Murani, Nares Trakooljul, Frieder Hadlich, Klaus Wimmers

Institution: Research Institute for Farm Animal Biology (FBN)

Language: English

Topic: Stress Responses and Cortisol

Subfield: Behavioral Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,880

Funders: Deutsche Forschungsgemeinschaft, Leibniz-Institut für Nutztierbiologie

Award: Untersuchung der Auswirkungen einer natürlichen GainofFunctionSubstitution im porcinen GlukokortikoidRezeptor auf die Regulation der HPAAchse, den GlukokortikoidRezeptorSignalweg und auf die Stressreaktivität

OpenAlex ID: W4405316072

FWCI: 0.205

Cites: 68

Cited by: 1

Related to: 10