Work

Framework Nucleic Acid‐Based Selective Cell Catcher for Endogenous Stem Cell Recruitment (Adv. Mater. 50/2024)

Year: 2024

Type: article

Abstract: Endogenous Stem Cell Recruitment Using the precise programmability of tetrahedral framework nucleic acids (tFNA), Yunfeng Lin, Taoran Tian, and co-workers introduce a novel strategy for endogenous stem cell enrichment. This strategy employs the MSC-targeting aptamer Apt19S, optimizing its distribution and topology on tFNA to address challenges like cellular internalization and low affinity, thereby improving MSC binding and capture efficiency. This acellular, regenerative platform holds great potential for various clinical applications in tissue regeneration. More details can be found in article number 2406118.

Source: Advanced Materials

DOI: 10.1002/adma.202470400

Authors: Xingyu Chen, Ziang Xu, Yang Gao, Ye Chen, Wumeng Yin, Zhiqiang Liu, Weitong Cui, Yong Li, Jiafei Sun, Yuting Yang, Wenjuan Ma, Tao Zhang, Taoran Tian, Yunfeng Lin

Institutions: Sichuan University, West China Hospital of Sichuan University, State Key Laboratory of Oral Diseases

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4405325267

FWCI: 0.232

Cites:

Cited by: 2

Related to: 10