Work

Impact of Race and Ethnicity on Clinical Outcomes of Collagenase Clostridium histolyticum in Patients With Peyronie’s Disease Across Kaiser Permanente Southern California Database

Year: 2024

Type: article

Abstract: INTRODUCTION: (CCH) injection is an effective intervention for treatment of Peyronie's disease (PD). While CCH efficacy has been demonstrated in White populations, little is known about treatment efficacy in Black and Hispanic populations. METHODS: This study examined efficacy of intralesional CCH in a racially diverse population in a large integrated health care system over 15 years. Treatment efficacy was defined as percent change in penile curvature abnormality from baseline after up to 4 treatment cycles. RESULTS: = .0004). Almost half of the Hispanic subgroup (48%) reported needing an interpreter for health appointments. DISCUSSION: This is the largest postmarket analysis of CCH treatment outcomes in a racially diverse PD population. Though there were no significant differences in treatment outcomes by race and ethnicity, Hispanic men were significantly less likely to complete 4 cycles of injection therapy. One possible explanation is a language barrier, which prevented future follow-up treatment. CONCLUSION: The use of CCH treatment for PD is an effective option for racially diverse patient populations.

Source: The Permanente Journal

DOI: 10.7812/tpp/24.111

Authors: Michael O Okene, Priyanka Achalu, Tung-Chin Hsieh, Hossein Mirheydar

Institutions: Kaiser Permanente Bernard J. Tyson School of Medicine, University of California San Diego, Kaiser Permanente Baldwin Park Medical Center

Language: English

Topic: Dupuytren's Contracture and Treatments

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Reduced inequalities

Open Access status: hybrid

OpenAlex ID: W4405335540

FWCI:

Cites: 1

Cited by:

Related to: 10