An in vitro Study into Antioxidant, Antibacterial, and Toxicity Impacts of Artocarpus altilis Leaf Extract
Year: 2024
Type: article
Abstract: Artocarpus altilis (Parkinson) Fosberg, which was first discovered in 1769, mainly grows in subtropical and tropical areas.This plant is famous for having multiple applications in Asia, where people use fruits for food, leaves for drinks, and trunks for wood. A. altilis is also famous for treating human diseases such as diarrhea, dysentery, and other intestinal diseases.Various phytochemicals are determined in this plant and predicted to create biological activities.The bio-effects of the leaf extract were evaluated in order to supply scientific evidence contributing to this plant into the orthodox medical application.A free radical scavenging assay, a reducing power assay, a broth-diluted assay, and a brine shrimp lethality assay were performed to evaluate the extract's antioxidant, antibacterial, and toxicity capacities.The extract was clarified to be able to scavenge the free radical DPPH (EC50 = 48.65 ± 1.86 µg/mL) and active ABTS (EC = 29.27± 4.38 µg/mL) as well as reduce the Fe 3+ into Fe 2+ in solution.Moreover, the anti-positive gram bacteria were detected as an activity of the extract, also causing death to the brine shrimp with an LC50 of 87.68 ± 4.67 µg/mL.Hence, the bio-activities of the A. altilis extract were initially demonstrated to inhibit Gram-positive microorganisms and balance the activity of redox.
DOI: 10.54319/jjbs/170407
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4405366236