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Advances in basic and translational research into nasopharyngeal carcinoma

Year: 2024

Type: article

Abstract: According to the International Cancer Research Institute of the World Health Organization data, nasopharyngeal carcinoma (NPC) remains a significant health concern, particularly in regions such as Southeast Asia and southern China. Recently, substantial progress has been made in the field of basic and translational research on NPC, enhancing our understanding of the molecular mechanisms underlying the disease and paving the way for precise therapeutic approaches. This review summarizes the advances in NPC research, focusing on key areas that include radiotherapy and chemotherapy resistance and tumor metastasis, microenvironment, metabolism, microbiome, and biomarkers. Additionally, future research directions in NPC are discussed to provide valuable insights to advance the field further.

Source: Oncology and Translational Medicine

DOI: 10.1097/ot9.0000000000000071

Authors: Zhe Li, Yupei Chen, Jun Ma

Institutions: Sun Yat-sen University, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China

Language: English

Topic: Head and Neck Cancer Studies

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405368060

FWCI: 2.345

Cites: 57

Cited by: 6

Related to: 10