Work

Opinion: contemporary insights into the efficacy of Preimplantation Genetic Testing for Aneuploidy (PGT-A) by mining the Society for Assisted Reproductive Technology (SART) database

Year: 2024

Type: article

Abstract: Chromosome abnormalities (predominantly aneuploidy: extra (trisomy) or missing (monosomy) chromosomes) are collectively the leading cause of in vitro fertilisation (IVF) failure, pregnancy loss and developmental delay in humans. 1 As such, the technique of PGT-A has been practiced for over 30 years2 to try and mitigate this problem. The purpose of PGT-A is to treat patients at risk of transmitting aneuploidy, especially in high-risk referral categories. The hope is that live birth rates (LBR) and miscarriage rates following IVF can be improved through its use.

Source: BMJ connections.

DOI: 10.1136/bmjccgg-2024-000003

Authors: Santiago Munné, Darren K Griffin

Institutions: Kasetsart University, University of Kent

Language: English

Topic: Prenatal Screening and Diagnostics

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405385437