Work

Screening of novel lactic acid bacteria with high induction of immunoglobulin A production, dendritic cell activation, and interleukin-12 production

Year: 2024

Type: article

Abstract: In this study, we screened 308 lactic acid bacteria strains for high immunoglobulin A (IgA) production, dendritic cell activation, and interleukin-12 (IL-12) production using human-derived cells. Among them, Lactobacillus helveticus GCL1815 demonstrated superior performance in all aspects, indicating its remarkable potential for immunomodulatory functions in both innate and adaptive immunity.

Source: Bioscience Biotechnology and Biochemistry

DOI: 10.1093/bbb/zbae196

Authors: Keigo Tsuruno, Takashi Mawatari, Yukimasa Tanaka-Azuma, Atsushi Yamatsu, Soichi Tanabe

Institution: Ezaki Glico (Japan)

Language: English

Topic: Probiotics and Fermented Foods

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4405390834