Year: 2024
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: To investigate the relationship between biological, psychological, and social factors underlying Burning Mouth Syndrome (BMS). SUBJECTS AND METHODS: A case (n = 40) and control (n = 42) study containing 80 variables was examined using two network models based on regularized partial correlations (n = 82). RESULTS: The structure of the associative pathways with the BMS was revealed. Direct associations involved Gastrointestinal Alterations (0.23), Vitamin D Deficiency (0.29), Musculoskeletal Alterations (0.29), Symptom Severity Score 2 (SSS2) (0.22), Cortisol Variation (0.10), Interpersonal Sensitivity (0.04), Hostility (0.03). Global Severity Index, Symptom Severity Score 1, Psychoticism, Obsession-Compulsion, Depression, Anxiety, and Somatization were indirectly related. The SSS2 was the most influential on BMS accuracy. CONCLUSIONS: Gastrointestinal alterations and vitamin D deficiency show a significant influence on BMS while cortisol mediates in multiple associative pathways between musculoskeletal alterations, gastrointestinal alterations, vitamin D deficiency, non-restorative sleep, fatigue, and cognitive problems. In addition to anxiety and depression, psychoticism, interpersonal sensitivity, and hostility stand out as psychological factors that seem to be related to a lack of vitamin D. None of the factors studied seem to have a relevant predictive potential for BMS, except for nonspecific symptoms of central sensitization.
Source: Oral Diseases
DOI: 10.1111/odi.15219
Authors: Oscar Gabriel Castaño‐Joaqui, Laura Jiménez Ortega, Rocío Cerero Lapiedra, Marta Monteserín Matesanz, Adelaida África Domínguez Gordillo
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,840
OpenAlex ID: W4405399003