Moisture sorption characteristics of crystalline and amorphous 2'-fucosyllactose, a human milk oligosaccharide
Year: 2024
Type: article
Abstract: The moisture sorption characteristics of crystalline and amorphous forms of 2′-fucosyllactose (2′-FL) were investigated and compared with those of two forms of lactose. The moisture sorption isotherms showed that, relative to crystalline α-lactose monohydrate (α-LM), crystalline 2′-FL was more susceptible to moisture sorption. Crystalline 2′-FL exhibited a lower deliquescence point (89.8 %) but threefold greater water solubility (57.1 %) than crystalline α-LM at 25 °C. Time-dependent moisture sorption, X-ray diffraction, and scanning electron microscopy analyses confirmed that amorphous 2′-FL underwent moisture-induced crystallisation (similar to amorphous lactose), but required more humid conditions ( a w > 0.53; a w > 0.33 for amorphous lactose) due to lower molecular mobility. Dynamic oscillatory rheology showed that amorphous 2′-FL exhibited a higher sticky point temperature ( T s ) compared with amorphous lactose at any given a w , and T s decreased from 78.9 °C to 43.6 °C as a w increased from 0.23 to 0.53 due to the plasticizing effect of moisture. • Crystalline 2′-FL was more susceptible to moisture sorption than crystalline α-LM. • Crystalline 2′-FL exhibited a lower deliquescence point than crystalline α-LM. • Amorphous 2′-FL underwent moisture-induced crystallisation. • Amorphous 2′-FL had higher sticky point temperatures than amorphous lactose. • Amorphous 2′-FL showed less moisture-sensitive stickiness than amorphous lactose.
Source: Food Chemistry
Authors: Sungahm Ahn, Hee Chung, Dong Zhao, Donghwa Chung
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
SDG: Zero hunger
Open Access status: hybrid
Estimated APC paid: $4,620
OpenAlex ID: W4405420940