Work

Dynamics of Left Ventricular Shape in Preterm Infants: Functional Geometry and Geometric Morphometrics

Year: 2024

Type: conference-paper

Abstract: The aim of this study was to describe the left ventricular (LV) shape and its deformation during the cardiac cycle in extremely low and very low birth weight preterm at 1-3 days of age compared to term infants using functional geometry (FG) and geometric morphometrics (GM) methods.LV shape and spatio-temporal heterogeneity of LV wall motion throughout the cardiac cycle were evaluated by FG methods.We also obtained cardiac shape descriptors using GM framework, which allowed us to focus solely on inter-patient differences in shape changes associated with the cardiac cycle.Statistically significant differences between groups were observed in LV wall motion spatial heterogeneity (higher in preterm), the sphericity (lower in preterm) and shape complexity (higher in preterm) in late diastole, the first two components of the shape space obtained by GM.Thus we have demonstrated pronounced differences in shape change dynamics between term and preterm infants which can be further tackled and investigated in the GM framework.

Source: Computing in cardiology

DOI: 10.22489/cinc.2024.266

Authors: Tatiana Chumarnaya, Roman Rokeakh, Evgeniya Gusarova, Lev Malishevskii, Olga Solovyova

Institutions: Ural Federal University, Institute of Immunology and Physiology

Language: English

Topic: Congenital Heart Disease Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Russian Science Foundation