Work

Overcoming triple-negative breast cancer (TNBC) resistance to oncolytic virotherapy by histone deacetylase inhibitor, trichostatin A

Year: 2022

Type: preprint

Abstract: "Triple-negative breast cancer (TNBC) is a tumor classification that lack receptors for the hormones estrogen, progesterone and HER2 protein. These malignancies are characterized to be of poor prognosis, refractoriness to conventional therapy and high rates of recurrence. Virotherapy with oncolytic adenovirus (OAd) consists of cancer selective viruses that replicate, spread, and kill cancer cells by oncolysis, without affecting the normal cells."--Introduction.

Source: MOspace Institutional Repository (University of Missouri)

DOI: 10.32469/10355/94660

Authors: Martin R. Ramos-Gonzalez, Haval Shirwan, Esma S. Yolcu, Jorge G. Gomez-Gutierrez

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4405439257

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