Work

Synthesis and characterization of F127-Glu@ZnO nanogel material for cisplatin drug delivery application

Year: 2024

Type: article

Abstract: A novel F127-Glu@ZnO nanogel was synthesized for cisplatin delivery by functionalizing ZnO nanoparticles with L-glutamic acid (Glu) and grafting Pluronic onto Glu via urethane linkages. FT-IR and ¹H-NMR confirmed successful synthesis, while TEM characterized morphology. The nanogel exhibited pH-responsive drug release, accelerating cisplatin release in acidic environments. This suggests its potential as a smart drug delivery system for improving therapeutic efficacy and reducing side effects in cancer treatment.

Source: Journal of Military Science and Technology

DOI: 10.54939/1859-1043.j.mst.fee.2024.237-242

Authors: Nguyen Ngoc Son, Vu Minh Thanh, Nguyen Thi Huong

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405481100

FWCI: 0.084

Cites: 14

Cited by: 1

Related to: 10