eLife Assessment: Characterization of cancer-driving nucleotides (CDNs) across genes, cancer types, and patients
Year: 2024
Type: peer-review
Abstract: This valuable study is a companion to a paper introducing a theoretical framework and methodology for identifying cancer-driving nucleotides (CDNs).The evidence that recurrent SNVs or CDNs are common in true cancer driver genes is convincing, with more limited evidence that many more undiscovered cancer driver mutations will have CDNs, and that this approach could identify these undiscovered driver genes with about 100,000 samples.
Source: eLife
Author: Detlef Weigel
Institution: Max Planck Institute for Biology
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,500
Funders: American Association for Cancer Research, National Natural Science Foundation of China, Sun Yat-sen University, Jinan University, Chinese Academy of Medical Sciences, Guangdong Provincial People's Hospital, Kunming Institute of Zoology, Chinese Academy of Sciences, Basic and Applied Basic Research Foundation of Guangdong Province
OpenAlex ID: W4405493363