Work

Skeletal Stem Cells: A Basis for Orthopaedic Pathology and Tissue Repair

Year: 2024

Type: article

Abstract: ➢ Skeletal stem cells (SSCs) continually replenish mature cell populations to support skeletal homeostasis.➢ SSCs repopulate by self-renewal, have multilineage potential, and are long-lived in vivo.➢ SSCs express specific combinations of cell surface markers that reflect their lineage identity.➢ SSCs adapt to their anatomic environment to support regional differences in skeletal behavior and pathology.

Source: Journal of Bone and Joint Surgery

DOI: 10.2106/jbjs.24.00905

Authors: Ting Cong, Kyle W. Morse, Branden R. Sosa, Joseph M. Lane, Scott A. Rodeo, Matthew B. Greenblatt