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Temporal Trends of Ischemic Stroke Risk in Patients With Incident Atrial Fibrillation Before Anticoagulation

Year: 2024
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Atrial fibrillation (AF) is a major risk factor for ischemic stroke (IS), but whether the magnitude of this risk has changed over time is unknown. OBJECTIVES: This study sought to investigate temporal trends in IS rates in patients with incident AF before oral anticoagulant agent (OAC) therapy. METHODS: -VA) score values. RESULTS: -VA score of 1 was 8.2 events per 1,000 patient-years and remained stable across the study period. CONCLUSIONS: The initial IS risk in AF patients, before the initiation of OAC therapy, has decreased by 25% between 2007 and 2018 despite an increase in both age and stroke risk scores. The decrease has been most pronounced in older women with high stroke risk scores.
DOI: 10.1016/j.jacep.2024.10.029
Authors: Konsta Teppo, K.E. Juhani Airaksinen, Olli Halminen, Jussi Jaakkola, Jari Haukka, Elis Kouki, Alex Luojus, Jukka Putaala, Birgitta Salmela, Miika Linna, Aapo L. Aro, Pirjo Mustonen, Juha Hartikainen, Gregory Y.H. Lip, Mika Lehto
Institutions: University of Turku, Turku University Hospital, Aalto University, University of Helsinki, Helsinki University Hospital, Päijät-Hämeen Keskussairaala, University of Eastern Finland, Kuopio University Hospital, University of Liverpool, Liverpool Heart and Chest Hospital, Liverpool John Moores University, Aalborg University, Jorvi Hospital
Language: English
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $4,750
OpenAlex ID: W4405519946
FWCI: 2.137
Cites: 41
Cited by: 8
Related to: 10