Incidence and Clinical Course of Post-infectious Irritable Bowel Syndrome in Patients Admitted to University Hospitals: 1-year Prospective Follow-up Study
Year: 2024
Type: article
Study design: Observational Study
Abstract: Background/Aims: Post-infectious irritable bowel syndrome (PI-IBS) is characterized by chronic gastrointestinal symptoms that arise following an episode of infectious enteritis. The incidence rates vary, ranging from 5% to 32% and the risk factors are not well known. We aim to investigate the incidence and risk factors of PI-IBS in enteritis patients admitted to university hospitals in Korea. Methods: This multi-center prospective study was conducted in patients hospitalized for infectious enteritis. Each patient underwent 1 outpatient visit and 3 telephone surveys during the first year after discharge to determine if PI-IBS occurred within the follow-up period. Results: = 0.018) were independent risk factors for diarrhea lasting ≥ 3 months after enteritis. Conclusions: The incidence of PI-IBS in Korea was relatively low, and most cases improved over time. No risk factors associated with the development of PI-IBS were found. However, persistent diarrhea after enteritis was associated with female sex, EPEC infection, and severe or long-lasting enteritis. IBS symptoms may persist after severe enteritis but usually improve with time.
DOI: 10.5056/jnm24018
Authors: Jae Gon Lee, Sang Pyo Lee, Hyun Joo Jang, Sea Hyub Kae, Woon Geon Shin, Seung In Seo, Hyun Lim, Ho Suk Kang, Jae Seung Soh, Chang Seok Bang, Young Joo Yang, Gwang Ho Baik, Jin Bae Kim, Yu Jin Kim, Chang Kyo Oh, Hallym Gastrointestinal Study Group
Institutions: Hallym University, Hallym University Kangnam Sacred Heart Hospital, Hallym University Dongtan Sacred Heart Hospital, Hanyang University Seoul Hospital, Hanyang University, Kangdong Sacred Heart Hospital, Hallym University Sacred Heart Hospital, Hallym University Chuncheon Sacred Heart Hospital
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405534638