Work

Trypsinized suction blister

Year: 2024

Type: article

Abstract: Suction blister epidermal grafting (SBEG) is a standard technique for treating vitiligo on challenging areas like fingertips and lips but often results in pigment halos and difficulties with small, curved surfaces. We propose a modified SBEG technique, utilizing trypsinization of one blister graft to improve melanocyte spread and reduce peri-graft halo. Trypsin ethylenediaminetetraacetic acid (EDTA) solution is introduced into a selected blister, creating a cell suspension applied to dermabraded gaps and peripheries, including eyelid margins. At 5-month follow-up, complete re-pigmentation with no halo effect was achieved, indicating this modified approach's potential in enhancing SBEG outcomes for complex sites.

Source: Journal of Cutaneous and Aesthetic Surgery

DOI: 10.25259/jcas_2_24

Authors: Suman Patra, Shubham Kumar, Maninder Kaur

Institution: All India Institute of Medical Sciences Jodhpur

Language: English

Topic: melanin and skin pigmentation

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405545916

FWCI:

Cites: 2

Cited by:

Related to: 10