Work

Olanzapine-induced hypertriglyceridemia in cancer care: A silent metabolic risk

Year: 2024

Type: article

Abstract: Olanzapine (Zyprexa), an atypical antipsychotic, is used off-label for managing nausea in advanced cancer patients but is linked to severe metabolic side effects, including hypertriglyceridemia. This case involves a metastatic gastric carcinoma patient with no known metabolic disorder who developed critically elevated triglycerides (2898 mg/dL) after starting olanzapine for nausea. Her lipid levels significantly improved with medical management, allowing her to proceed for apheresis for the planned CAR-T treatment. This case underscores the need for vigilant metabolic monitoring in patients on Olanzapine (Zyprexa), even those without known risk factors, to prevent serious complications.

Source: Current Problems in Cancer Case Reports

DOI: 10.1016/j.cpccr.2024.100345

Authors: Bilal Kazi, Imaan Rumani, Marzooka Nazim Chishti Kazi, Prashant Manohar Gaikwad

Language: English

Topic: Schizophrenia research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $830

OpenAlex ID: W4405556140

FWCI: 0.269

Cites: 8

Cited by: 1

Related to: 10