An Unusual Case of Intraosseous Desmoplastic Fibroblastoma (Collagenous Fibroma) of the Mandible
Year: 2024
Type: article
Study design: Case Report
Abstract: Desmoplastic fibroblastoma (collagenous fibroma) is a rare, benign fibroblastic/myofibroblastic tumor that usually arises in the subcutaneous and intramuscular tissues. This tumor type has rarely been described to arise primarily in bones. This is a case of intraosseous desmoplastic fibroblastoma occurring in the mandible of a 35-year-old woman that was detected incidentally during a routine dental examination. The patient underwent surgical excision of the lesion. Microscopic examination demonstrated a paucicellular fibro-collagenous spindle cell neoplasm that showed a fibroblastic/myofibroblastic immunophenotype, consistent with desmoplastic fibroblastoma of the bone. The case presents an extremely rare intraosseous manifestation of an uncommon soft tissue tumor, highlighting its diverse anatomical and compartmental distribution.
Source: Cureus
DOI: 10.7759/cureus.75904
Author: Rana Al-Zaidi
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405561267