Terahertz photoneuromodulation of lateral orbitofrontal cortex neurons ameliorates stress-induced depression and cognitive impairment
Year: 2024
Type: article
Abstract: ) compared to those treated with antidepressants. This led to marked improvements in depressive-like behaviors and cognitive function. Furthermore, THz modulation of OFC activity recapitulated the effects of chemogenetic inhibition, underscoring the OFC's pivotal role in regulating depressive states. This research unveils THz photoneuromodulation as a promising, safe, rapid-acting, and durable neurotherapeutic strategy addressing persistent unmet needs in depression treatment.
Source: Fundamental Research
Authors: Yuanyuan He, Jing Ma, Yun Yu, Junkai Yin, Ge Gao, Yifang Yuan, Hao Ruan, Xueqing Yan, Zihua Song, Chao Chang
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4405564235