Work

Successful healing of chronic venous ulcer using zinc oxide nanoparticles and compression therapy in a 75-year-old Syrian female: a case report

Year: 2024

Type: article

Abstract: Introduction: Chronic venous disease is a commonly underdiagnosed condition that gradually diminishes a patient's quality of life and imposes a growing burden on healthcare resources. Venous leg ulcers (VLUs) arise as a complication of chronic venous insufficiency and represent the most prevalent type of slow-healing wound in the lower extremities. Case presentation: In this case report, we present the successful treatment of a 75-year-old woman with a chronic venous ulcer caused by chronic deep venous insufficiency. The patient had been struggling with an unresponsive venous leg ulcer for 7 years with no improvement from previous treatments. A three-layer Unna boot treatment, including (ZnO NPs) and a two-component compression system was applied, and significant ulcer reduction was observed. Discussion: ZnO NPs impregnated bandages, like those found in an Unna boot, offer compression by wrapping gauze dressing impregnated with ZnO NPs around the patient's leg forming a semi-solid mold around the extremity. A more efficient treatment approach could lead to fewer clinic visits, thereby reducing healthcare expenses by enhancing the method of managing venous ulcers through a combination of compression and simple, cost-effective surface dressing materials. It's worth noting that ZnO NPs have demonstrated significant benefits for wound healing. Conclusion: Utilizing ZnO NPs alongside compression therapy has proven highly effective, accelerating healing and offering a cost-effective solution. Further research is needed to study the safety of ZnO NPs.

Source: Annals of Medicine and Surgery

DOI: 10.1097/ms9.0000000000002881

Authors: Hiba Shreiki, George Bashour, Houssam Kinjo

Institution: Latakia University

Language: English

Topic: Diagnosis and Treatment of Venous Diseases

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,850