Work

Systemic Absorption of Oral and Rectal Vancomycin in a Critically Ill Patient: A Case Report

Year: 2024

Type: article

Abstract: Enteral administration of vancomycin is the standard treatment for Clostridioides difficile (Clostridium difficile) colitis and is presumed to have no systemic absorption. In critically ill patients, however, especially with multi-organ failure, enteral absorption of vancomycin is unpredictable and can cause severe toxicity if it remains unrecognized. We therefore report a case of systemic absorption of enteric vancomycin in a patient with severe C. difficile colitis.

Source: Cureus

DOI: 10.7759/cureus.76008

Authors: Rastko Rakočević, Keith Guevarra

Institutions: University Hospital, Newark, Los Angeles Medical Center, Rutgers New Jersey Medical School

Language: English

Topic: Clostridium difficile and Clostridium perfringens research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405569031