Year: 2024
Type: article
Abstract: New genes arise from duplication followed by divergence. The most common fate of a duplication is one copy is deleted to return to a single copy. But if divergence occurs, the function of the gene can be split between the two copies, which is called subfunctionalization, or a new function can arise, which is called neofunctionalization. Changes in expression between the two copies does not necessarily suggest that subfunctionalization has occurred. In this commentary, the caveats and criteria for subfunctionalization are discussed.
Source: G3 Genes Genomes Genetics
Author: James A Birchler
Institution: University of Missouri
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,790
Funder: National Science Foundation
OpenAlex ID: W4405571590