Year: 2024
Type: article
Abstract: The reactivity of our recently disclosed hypervalent iodine reagents (HIRs) bearing a benzylamine with in situ-generated sulfenate salts was investigated. Under the studied conditions sulfonamides have been obtained in up to 52% yield. This reaction has been extended to a variety of HIRs and sulfenate salts to explore the different reactivity of these new reagents. A plausible mechanism is proposed, suggesting a possible radical pathway.
DOI: 10.3762/bjoc.20.272
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
Awards: G1167214205, G1240268737, UID/BIA/04004 .: Centro de Ecologia Funcional, G1509028180, G1516346500, G1578237752, G1707751058, G1763632427, Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos, Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos, G2673245850, G2734793695, G274581676, G2756637201, G2783038177, G2814222956, G299573334, G3720188711, Investigation of novel sulfonyl-containing small-molecules: synthesis and screening, G3840324753, G3891694003, G4046065984, G437104828, G4378797157, G491858407, G5102570033, G5224927334, G547185811, G5868090805, G6119126181, G6193589897, G6463117426, Biologia Estrutural Moderna: Recursos para impulsionar a Cristalografia de Raios-X "in-house", G6997658380, G7965899483, G8059013210, G8213652065, G824076568, Hi2E-Synth: Iodo hipervalente para expandir o espaço químico e aceder a moléculas sintéticas nitrogenadas, Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos, G977537520
OpenAlex ID: W4405575463