Work

Tyrosine kinase ABL1 as a promising molecular target for anticancer drugs 17

Year: 2024

Type: article

Abstract: Tyrosine kinase ABL1 plays an important role in many key cellular processes linked to growth, proliferation, differentiation, survival, apoptosis, cell motility, adhesion, etc.However, this protein kinase is also associated with the development of several oncological diseases.In this review we summarize the literature data on the ABL1 structure, function, the role in cancer and known inhibitors of the kinase.K e y w o r d s: protein kinase ABL1, cancer, inhibitor.

Source: Biopolymers and Cell

DOI: 10.7124/bc.000b09

Authors: O. A. Chuk, S. V. Antonenko, L. V. Pletnova, S. M. Yarmoluk, G. P. Volynets

Institutions: Kyiv Academic University, Institute of Molecular Biology and Genetics

Language: English

Topic: Cancer Mechanisms and Therapy

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405578466