Determination of Tumor Cell Sensitivity to Cytostatic Agents on the Example of Cultures of Non-Small Cell Lung Cancer in vitro
Year: 2024
Type: article
Abstract: Chemoresistance is a key factor restricting the use of anticancer drugs in the treatment of non-small cell lung cancer. Data on the sensitivity of tumor cells in vitro to prescribed cytostatic drugs can facilitate the prediction of cell chemoresistance for selecting optimal drugs aimed at curbing the disease and suppressing tumor growth. It is known that methods for assessing the sensitivity of cells depend on their metabolic activity. In view of this, we conducted a preliminary experiment to assess the proliferative activity of cells, which allowed us to select the concentration of cells in the exponential growth phase and calibrate the method for cell cultures.
Source: Journal Biomed
Authors: K. A. Makaveeva, E. G. Kirkina, D. S. Gaidai
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405588435