Evaluation of the chitin-glucan-melanin complex from fomes fomentarius for stopping bleeding and providing first aid for laceration and burns in combat conditions
Year: 2024
Type: article
Abstract: A fine-fiber composite material based on chitin-glucan-melanin complex (ChGMC) from the fungus Fomes fomentarius (Ordinarius tin, Basidiomycetes family) is not inferior to the best samples of surgical cotton in terms of hygroscopicity and surpasses it in its ability to rapidly stop bleeding and numb wounds. This material quickly stops bleeding from large vessels, does not penetrate into the tissues from the surface of the wound, and over time is displaced from it thanks to the stimulation of cell regeneration, accelerates the recovery of damaged tissues and reduces the mass of scar tissue. The synergistic effect of chitin/chitosan, beta-glucans and melanin disinfects purulent wounds – neutralizes various bacteria, pathogenic micromycetes and wound viruses in the wound. The aseptic mechanism of action of ChGMC is not toxic for the cells of the host organism and at the same time is directed at the binding of toxic products. ChGMC is not inferior to the best samples of surgical cotton in terms of hygroscopicity and surpasses it in its ability to rapidly stop bleeding and numb wounds. Over time, ChGMC is displaced from the wound, accelerates the recovery of damaged tissues, reduces the mass of scar tissue, and almost halves the duration of treatment. ChGMC showed its high efficiency in the treatment of infected surgical and burn wounds, as well as trophic ulcers. The thin fiber structure of the product and a huge specific surface area (more than 1000 m2/g of material) make it possible to create materials for covering deep wounds, powder-like products for covering damaged skin, foam-like napkins for closing the wound surface, and others
Source: EUREKA Life Sciences
Language: English
Topic: Wound Healing and Treatments
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $107
OpenAlex ID: W4405596709