Renal Involvement in Diffuse Large B-cell Lymphoma
Year: 2024
Type: article
Study design: Case Report
Abstract: A BSTRACT The association between renal disease and hematolymphoid neoplasms is increasingly recognized, with kidneys often affected through mechanisms such as acute tubular necrosis, tumor lysis syndrome, and lymphocytic infiltration of kidney parenchyma (LIK). This case report presents a male patient in his fifties with no previous comorbidities, who initially presented with fever, abdominal pain, weight loss, and pedal edema, leading to the discovery of bilateral obstructive nephropathy. Imaging revealed conglomerated retroperitoneal mass infiltrating the pancreas, small bowel loops, bilateral kidneys, and ureter. A diagnosis of diffuse large B-cell lymphoma was made following a biopsy of the retroperitoneal mass, and the patient was started on R-mini-CHOP chemotherapy. Despite initial stabilization of renal function, the patient was lost to follow-up.
Authors: Shashikant Saini, Jasmine Sethi, Vignesh Subramani, Yamini Mathur, Suvradeep Mitra
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4405603448