Year: 2024
Type: article
Abstract: An approach was developed to the synthesis of triterpene C3-nitrones containing the amide function at C28-position, new derivatives of pentacyclic triterpenoids of the lupan series. Diastereomeric triterpene 3β- and 3α-hydroxylamines obtained by reduction of oxime based on betulonic acid isopropylamide with NaBH3CN in a solution of 2 M HCl in MeOH were used as starting compounds. Nitrones were synthesized by condensation of hydroxylamines with substituted benzaldehydes in dichloromethane in the presence of Na2SO4.
Source: Журнал Общей Химии
Institution: Ufa Institute of Chemistry
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4405622120