Year: 2024
Type: article
Study design: Observational Study
Abstract: BACKGROUND: We investigated the prevalence and clinical characteristics of type 2 diabetes mellitus in lean Korean adults. METHODS: We analyzed data from the Korea National Health and Nutrition Examination Survey 2001-2021 among adults aged ≥ 19 years. Trend analyses between 2001 and 2019-2021 (n = 89,720) and comparative analyses of multiple clinical characteristics between patients with type 2 diabetes with and without overweight/obesity were conducted (n = 2,284). RESULTS: ) increased from 6.6 to 8.8%, representing a 33.3% increase. This was a similar extent of increase of type 2 diabetes associated with being overweight or obese (12.1-16.3%, + 34.7%). The increase in the prevalence of lean type 2 diabetes was more pronounced among females, while the increase among those who were overweight or obese was more pronounced among males than their counterparts. Although the overweight/obese type 2 diabetes group (T2DM group) showed more risk factors for cardiovascular disease, the lean T2DM group had lower insulin levels and reduced muscle mass and strength. CONCLUSIONS: The prevalence of lean type 2 diabetes among Korean adults is increasing, at a rate similar to type 2 diabetes in overweight/obese individuals. Patients with lean type 2 diabetes showed decreased beta-cell function and sarcopenia. These findings emphasize the need for tailored management strategies for lean type 2 diabetes given its characteristics and rising prevalence.
Source: BMC Public Health
Authors: Ji Min Kim, Kyoung Hye Joung, Hyun Jin Kim, Bon Jeong Ku, Sukyoung Jung, Ju Hee Lee
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,190
OpenAlex ID: W4405637771