Work

Hepatic Artery Infusion Pump Therapy in Unresectable and Resectable Liver Tumors

Year: 2024

Type: article

Abstract: Hepatic artery infusion (HAI) chemotherapy is a regional, intra-arterial treatment of hepatic malignancies, delivering high-dose floxuridine directly to the liver. The rationale for HAI is based on the dominant blood supply of liver tumors from the hepatic arteries and near complete first-pass hepatic extraction of certain chemotherapeutic agents, which limits systemic toxicity. Although HAI chemotherapy is most commonly used among patients with colorectal liver metastases, it is now being more frequently employed for other disease processes such as intrahepatic cholangiocarcinoma and hepatocellular carcinoma as well. In addition, HAI chemotherapy is most often used in the setting of unresectable hepatic malignancies.

Source: Advances in Oncology

DOI: 10.1016/j.yao.2024.11.002

Authors: Lauren M. Janczewski, Ryan P. Merkow

Institutions: Northwestern University, University of Chicago

Language: English

Topic: Hepatocellular Carcinoma Treatment and Prognosis

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,000