Identifying Pathogens in Sequencing Data
Year: 2012
Type: other
Abstract: I just read an interesting paper on pathogen discovery using next-generation sequencing data, recommended to me by Nick Loman. A previously described algorithm (PathSeq, Kostic et al) for discovering microbes by deep-sequencing human tissue uses computational subtraction, whereby the initial collection of reads is depleted of human DNA by consecutive alignment to the human reference using MAQ and BLAST.
DOI: 10.59350/208td-dr225
Author: Stephen Turner
Institution: University of Virginia
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4405648390