Work

Photoredox radical/polar crossover enables carbo-heterofunctionalization of alkenes: facile access to 1,3-difunctionalized nitro compounds

Year: 2024

Type: article

Abstract: radical-polar crossover photoredox catalysis. Employing geminal bromonitroalkanes as redox-active reagents with a wide range of O-centered nucleophiles allows rapid access to various 1,3-difunctionalized nitro compounds, including β-nitro ketones, 1,3-nitro alcohols, 1,3-nitro ethers as well as cyclic molecules.

Source: Chemical Communications

DOI: 10.1039/d4cc06005a

Authors: Subrata Patra, Vasiliki Valsamidou, Bhargav N. Nandasana, Dmitry Katayev

Institution: University of Bern

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funders: University of Bern, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Award: Development of a New Generation of Easy Accessible and Stable Reagents for Functional Group Transfer Reactions