Work

A case report and literature review: leiomyosarcoma or perivascular epithelioid cell neoplasm?

Year: 2024

Type: article

Abstract: The distinction between a uterine leiomyosarcoma (uLMS) and a perivascular epithelioid cell neoplasm (PEComa) can be quite challenging. Here we report a 39-year-old woman who underwent a hysteroscopic myomectomy. An intraoperative frozen section pathological examination revealed that the mass was likely to be a mesenchymal malignancy. After consultation with her family, a total hysterectomy and bilateral salpingo-oophorectomy were performed. Postoperative pathological examinations suggested leiomyosarcoma but a malignant PEComa cannot be completely excluded. Combining the present case and prior studies, we summarized the clinical manifestations, pathological features, genomic characterization, and treatment of LMS and PEComa.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2024.1499403

Authors: Zheng Chen, Xuan Zheng, Qin Lin

Institutions: Shanghai Jiao Tong University, International Peace Maternity & Child Health Hospital

Language: English

Topic: Uterine Myomas and Treatments

Subfield: Obstetrics and Gynecology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,295