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Toxic shock syndrome secondary to Group A Streptococcus infection: A case report

Year: 2024

Type: article

Abstract: Toxic shock syndrome secondary to Group A Streptococcus infection is a rare but serious cause of women's morbidity and mortality which can easily be misdiagnosed. A 37-year-old woman presented to the emergency department in a state of shock after a two-day history of abdominal pain, fever, diarrhoea and green vaginal discharge. Following extensive investigations, she was proved to have septic shock secondary to Group A Streptococcus pyogenes. Despite receiving intravenous antibiotics, she required explorative laparotomy, which proceeded to subtotal hysterectomy and bilateral salpingectomy. Subsequently, she developed multi-organ failure, disseminated intravascular coagulation, and limb ischemia requiring below-knee amputation of the right limb. She was discharged home. The aim of this report is to raise the awareness about toxic shock syndrome from Streptococcus pyogenes . A high index of suspicion is required to promptly diagnose this rare yet potentially fatal infection. • Invasive Group A Streptococcal infection can lead to maternal mortality. • Early diagnoses and timely intervention is crucial. • Multidisciplinary team is required for management of toxic shock syndrome. • Penicillin G along with Vancomycin or Clindamycin are the first line antibiotics.

Source: Case Reports in Women s Health

DOI: 10.1016/j.crwh.2024.e00679

Authors: Lara Strakian, Sonal Karia

Institution: Camden and Campbelltown Hospitals

Language: English

Topic: Streptococcal Infections and Treatments

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $860