Work

To study correlation between serum uric acid levels and the presence and degree of pre-clinical target organ damage in hypertensive population

Year: 2024

Type: article

Abstract: Background: High blood uric acid levels are associated with the emergence of hypertension.This study sought to examine the connection between elevated uric acid levels and the prevalence of organ damage in the hypertensive population because elevated uric acid levels are linked to hypertension.Materials and Methods: A sum of 200 patients (aged 32 to 70) were enrolled in this observational analytical case-control study between April 2021 and March 2022; of these, 150 had been diagnosed with untreated essential hypertension and were categorized into hypertension stages 1 and 2 according to the Joint National Committee's 7th and 8th editions of their guidelines. The control group consisted of 100 individuals of same age and gender who were otherwise healthy. Proformas were used to ensure all necessary clinical as well as laboratory information was recorded.Results: Among the hypertensive people in our research, 20% (N= 20) had LVH. In cases with LVH, serum uric acid levels averaged 5.92±1.39 mg/dL, but in those without the disease, they averaged 4.67±1.18 mg/dL (P<0 xss=removed N=12) N=20) N=30).> Conclusion: The hypertensive population was discovered to have greater blood uric acid levels than normotensives, and this was proven to be related to damage to target organs. This demonstrates that serum uric acid may be used in the hypertensive population as an early biochemical marker to determine the severity of organ damage.

Source: Panacea Journal of Medical Sciences

DOI: 10.18231/j.pjms.2024.141

Authors: Anurag Chaurasia, Balendra Shekhar Deepankar, Saurabh Burman

Institution: Shyam Shah Medical College

Language: English

Topic: Gout, Hyperuricemia, Uric Acid

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $48