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Intervertebral disc degeneration, inflammation, and bioactive lipids

Year: 2024

Type: article

Abstract: Intervertebral disc degeneration, inflammation, and bioactive lipids Intervertebral disc degeneration Intervertebral disc (IVD) degeneration is a common condition that is associated with significant morbidity. There is no specific treatment available for IVD except for surgical intervention. IVD is an inflammatory condition. I propose that IVD can be prevented and managed by local administration of lipoxin A4 (LXA4), a potent anti-inflammatory, cytoprotective and anti-osteoporotic metabolite formed from arachidonic acid (AA). Keywords: intervertebral disc, degeneration, lipoxin A4, arachidonic acid, inflammation.

Source: Recent trends in pharmacology.

DOI: 10.62425/rtpharma.1589019

Authors: Undurti Das, Ahmet Hacımüftüoğlu

Institution: Atatürk University

Language: English

Topic: Spine and Intervertebral Disc Pathology

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4405659722

FWCI:

Cites: 23

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Related to: 10