Work

Comparative analysis of paraclinical parameters in the as-sessment of osteoporosis: an integrative approach

Year: 2024

Type: article

Abstract: Osteoporosis is the most common metabolic bone disease with serious physical, psychosocial and economic consequences. It is a chronic, asymptomatic, progressive disease with multifactorial aetiology, characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue; A retrospective study was conducted, which included an initial cohort of 243 patients hospitalized between January 2023 and December 2023 at the County Emergency Hospital of Sibiu, Clinical Endocrinology Department ; Study results suggest that assessment of bone mineral density (BMD) remains a primary standard in the diagnosis of osteoporosis, as measured by T and Z scores from DXA densitometry. However, biomarkers such as total calcium, ionic calcium, vitamin D, phosphorus, PTH and bone degradation markers (e.g. Beta Crosslaps) play a significant role in assessing bone metabolism and identifying fracture risk; The study highlights the importance of screening in postmenopausal women and the need for calcium and vitamin D supplementation in patients with osteoporosis or osteopenia.

Source: Balneo and PRM Research Journal

DOI: 10.12680/balneo.2024.756

Authors: Oana Raluca Antonescu, Sinziana Calina Silisteanu, Alina Cristiana Venter, Mihaela Racheriu, Irina Elena Antonescu, Enikő Nemes-Nagy

Institutions: Lucian Blaga University of Sibiu, Ştefan cel Mare University of Suceava, University of Oradea, Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș

Language: English

Topic: Bone health and osteoporosis research

Subfield: Orthopedics and Sports Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $215