Work

Thoracic SMARCA4-Deficient Undifferentiated Tumor in a 40-Year-Old Male Welder With No Smoking History

Year: 2024

Type: article

Abstract: Thoracic SMARCA4-deficient undifferentiated tumor (TSDUT) is a rare and quite new classification of primary pulmonary malignancy. It is classified as a non-small cell lung cancer, typically associated with smoking, and is highly aggressive. Its clinical features, immunohistochemistry, and pathology are quite unique. In this case report, we describe the clinical course of TSDUT pancoast tumor in a 40-year-old male, without a substantial smoking history, but a significant history of occupational welding.

Source: Cureus

DOI: 10.7759/cureus.76203

Authors: Samuel MacDowell, Mufadda Hasan, Ahmad Ibrahim

Institutions: California University of Science and Medicine, Arrowhead Regional Medical Center

Language: English

Topic: Chromatin Remodeling and Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Arrowhead Regional Medical Center