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G3BP1/2-Targeting PROTAC Disrupts Stress Granules Dependent ATF4 Migracytosis as Cancer Therapy

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Year: 2024
Type: article
Source: Journal of the American Chemical Society
DOI: 10.1021/jacs.4c11146
Authors: Ting Dong, Fabao Zhao, Mengmeng Wang, Kaige Lyu, Jiayu Zhu, Wenru Zhang, Wenzhe Li, Yixuan An, Na Liu, Akhand Pratap Singh, Yue Yang, Dongwei Kang, Xiaohui Liu
Institutions: Shandong University, Chinese Academy of Medical Sciences & Peking Union Medical College
Language: English

Topic: Protein Degradation and Inhibitors
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Shandong University, National Natural Science Foundation of China, Taishan Scholar Project of Shandong Province, National Key Research and Development Program of China
Awards: G2146740759, G297583891, G4670015817, G5564223311, G706762625, G7935452240
OpenAlex ID: W4405693104
FWCI: 2.195
Cites: 38
Cited by: 19
Related to: 10
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