Work

The drosophila zinc finger Protein CG9609 interacts with the Deubiquitinating (DUB) module of the SAGA complex and participates in the regulation of Transcription

Year: 2024

Type: article

Abstract: In previous studies, we found that the zinc finger proteins Su(Hw) and CG9890 interact with the Drosophila SAGA complex and participate in the formation of the active chromatin structure and transcription regulation. In this research, we discovered the interaction of the DUB module of the SAGA complex with another zinc finger protein, CG9609. ChIP-Seq analysis was performed, and CG9609 binding sites in the Drosophila genome were identified. Analysis of binding sites showed that they are localized predominantly at gene promoters. The CG9609 protein has been shown to be involved in the regulation of gene expression.

Source: Molecular Biology

DOI: 10.31857/s0026898424040072

Authors: J. V. Nikolenko, M. M. Kurshakova, D. V. Kopytova, Y. A. Vdovina, N. E. Vorobyova, A. N. Krasnov

Institutions: Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Institute of Gene Biology

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W4405700228

FWCI:

Cites: 21

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Related to: 10