Work

Biomimetic Catalytic Remote Desaturation of Aliphatic Alcohols

Year: 2024

Type: article

Abstract: Herein we present photoinduced cobaloxime-catalyzed selective remote desaturation of aliphatic alcohols. This transformation, which proceeds efficiently at room temperature, facilitates the synthesis of valuable cyclic and acyclic allylic and homoallylic alcohols from readily available saturated aliphatic alcohols. Remarkably, this method obviates the need for external oxidants, noble metal catalysts, and phosphine ligands.

Source: Organic Letters

DOI: 10.1021/acs.orglett.4c03623

Authors: Kaiming Zuo, Jing Zhu, Faral Akhtar, Phong Dam, Luis Miguel Azofra, Osama El-Sepelgy

Institutions: Leibniz Institute for Catalysis, Universidad de Las Palmas de Gran Canaria

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500