Work

USP35 promotes breast cancer progression by regulating PFK-1 ubiquitination to mediate glycolysis

Year: 2024

Type: article

Abstract: This study identified that USP35 regulates the proliferation and glycolysis of breast cancer cells by mediating the ubiquitination level of PFK-1. The USP35/PFK-1 axis offers novel insight for the treatment of breast cancer.

Source: American Journal of Physiology-Cell Physiology

DOI: 10.1152/ajpcell.00733.2024

Authors: Weibin Lian, Chengye Hong, Debo Chen, Chuan Wang

Institutions: Fujian Medical University, Union Hospital

Language: English

Topic: Ubiquitin and proteasome pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Science and Technology Bureau of Quanzhou, Quanzhou City Science and Technology Program

Awards: G2273712093, G463351799

OpenAlex ID: W4405706161

FWCI: 1.04

Cites: 33

Cited by: 9

Related to: 10